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Fig. 7 | Acta Neuropathologica Communications

Fig. 7

From: Ganglioglioma deep transcriptomics reveals primitive neuroectoderm neural precursor-like population

Fig. 7

Ganglioglioma-infiltrating lymphocytes. A Lymphocyte feature plots of RNA concentrations for key general T lymphocyte (PTPRC, CD2, CD3 (CD3E, CD247)), T helper (CD4), cytotoxic T lymphocyte (CD8 (CD8A and CD8B), GZMA, PRF1), and regulatory T (IL2RA, FOXP3) markers. B Heatmap of lymphocyte RNA concentrations (log1p, base 2) for important markers of cytotoxic T lymphocyte state. C Heatmap of ganglioglioma cell expression of a priori important T cell modulating ligands. D Most (top 10 or fewer if Bonferroni-adjusted-p-value > 0.05) activated or suppressed GO pathways for lymphocyte clusters

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