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Table 2 Correlations between cholesterol esters and myelin markers in white matter. Spearman’s correlation coefficient (r) and p value are shown for associations between myelin markers and total cholesterol ester (CholE) or CholE(22:6) in frontal and parietal white matter. Significant correlations are in bold font

From: Disrupted myelin lipid metabolism differentiates frontotemporal dementia caused by GRN and C9orf72 gene mutations

 

Frontal white matter

Parietal white matter

 

Total CholE

CholE(22:6)

Total CholE

CholE(22:6)

 

r

p

r

p

r

p

r

p

PLP

-0.70

8.13 × 10 − 5

-0.79

1.53 × 10 − 4

-0.59

1.57 × 10 − 3

-0.66

2.74 × 10 − 4

MBP

-0.20

0.32

-0.48

0.014

0.12

0.55

0.12

0.55

CNP

-0.38

0.052

-0.43

0.030

-0.10

0.64

-0.25

0.23

Total ST

-0.39

0.0501

-0.52

6.07 × 10 − 3

-0.50

6.85 × 10 − 3

-0.52

4.27 × 10 − 3

Total Hex1Cer

-0.52

7.07 × 10 − 3

-0.46

0.020

-0.56

1.76 × 10 − 3

-0.51

5.73 × 10 − 3