Fig. 6

QUIVER image registry and cell identification. (A) Pseudocolored images were created from deconvolved single-channel IHC images. (B) The images were aligned using HALO software and generating a ten-channel image (nine antibodies and hematoxylin). (C) Cell/object count data, including marker co-expression, were generated using the object colocalization algorithm. Label colors coincide with representative color in markup image and merged image. Yellow dashed oval highlights a representative amyloid plaques and pink doted oval highlights a representative of tau tangles shown in all images