Table 2 Demographic, clinical and neuropathologic characteristics of postmortem brain donors

Sex (female) [n (%)]

4 (57.1)

4 (80.0)

4 (44.4)

3 (60.0)

0.380^†

Age at death (y) [mean (SD)]

74.0 (6.8)

81.0 (15.2)

74.2 (3.2)

77.6 (7.2)

0.433^#

PMI (h) [mean (SD)]

15.7 (7.5)

25.3 (9.2)

15.9 (5.9)

15.7 (9.1)

0.145^#

Age at diagnosis (y) [mean (SD)]

–

–

64.3 (6.5)

68.0 (7.8)

0.415^‡

Disease duration (y) [mean (SD)]

–

–

9.0 (7.4)

10.25 (3.4)

0.760^‡

Lewy inclusion pathology in ctx-fg

0.536*

 None [n (%)]

–

–

1 (11.1

1 (20.0)

 Few [n (%)]

–

–

4 (44.4)

3 (60.0)

 Moderate [n (%)]

–

–

3 (33.3)

–

 Many [n (%)]

–

–

1 (11.1)

1 (20.0)

LBD Braak stage

0.504*

 1 [n (%)]

–

–

–

–

 2 [n (%)]

–

–

–

–

 3 [n (%)]

–

–

–

–

 4 [n (%)]

–

–

1 (11.1)

1 (16.7)

7

 5 [n (%)]

–

–

2 (22.2)

–

 6 [n (%)]

–

–

6 (66.7)

4 (83.3)

LBD McKeith stage

0.472*

 Neocortical [n (%)]

–

–

5 (55.6)

4 (80.0)

 Limbic [n (%)]

–

–

2 (22.2)

–

 Brain stem predominant [n (%)]

–

–

1 (11.1)

1 (20.0)

AD Braak and Braak stage

0.363*

 I [n (%)]

3 (42.9)

3 (75.0)

4 (44.4)

4 (80.0)

 II [n (%)]

4 (57.1)

–

4 (44.4)

1 (20.0)

 III [n (%)]

–

1 (25.0)

1 (11.1)

–

 IV [n (%)]

–

–

–

–

 V [n (%)]

–

–

–

–

 VI [n (%)]

–

–

–

–

CERAD score

0.280*

 0 [n (%)]

7 (100.0)

5 (100.0)

8 (88.9)

3 (60.0)

 A [n (%)]

–

–

–

2 (40.0)

 B [n (%)]

–

–

1 (11.1)

–

 C [n (%)]

–

–

–

–