Fig. 9
From: Disturbed circadian rhythm and retinal degeneration in a mouse model of Alzheimer’s disease
Retinal functional alterations in 6- and 12-month-old wt and APP/PS1 mice. a Representative a- and b-waveforms of scotopic ERG recordings obtained from 6- to 12-month-old mice. b, c Quantitative analysis of amplitudes of a-waves in 6- and 12-months-old APP/PS1 and wt mice. d, e Quantitative analysis of amplitudes of b waves in 6- and 12-month-old APP/PS1 and wt mice. f Quantitative analysis of oscillatory potentials under scotophic conditions in 6- and 12-month-old APP/PS1 and wt mice. g Quantitative analysis of photophic ERG recorded from 6- to 12-month-old APP/PS1 and wt mice. Data are expressed as mean ± SEM. *p < 0.05; ***p < 0.001 using t-test (n = 6–9 mice per group). Scot 0.01 Scotopic test 0.01 cds/m2, Scot 3.0 Scotopic test 3.0 cds/m2, Scot 10.0 Scotopic test 10.0 cds/m2, OP Oscillatory potentials, Photo 3.0 Photopic test 3.0 cds/m2, wt wild type