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Fig. 1 | Acta Neuropathologica Communications

Fig. 1

From: The oncogenic circular RNA circ_63706 is a potential therapeutic target in sonic hedgehog-subtype childhood medulloblastomas

Fig. 1

Differential expression of circRNAs in medulloblastoma subgroups. A Circular RNA identification pipeline for the 126 medulloblastoma patients in four subgroups. B Raw total circular RNA counts across all 126 medulloblastoma patient samples. C Principal component clustering of 8925 highly expressed circRNAs. D–G The red and blue points and shades show significant circular RNAs for a group versus others with an adjusted p value < 0.05 and |log2 fold change|> 2. The box plot shows normalized expression for two significant upregulated circRNAs in WNT (D), SHH (E), G3 (F), and G4 (G) across all 126 medulloblastoma patients

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