Fig. 3

Illustration of differentially expressed genes in hPASC and the matched tumor cells. A Principal Components Analysis (PCA) showed a distinctive expression pattern between hPASCs (blue) and the matched tumor cells (red). B Volcano plot showed the distribution of the upregulated and downregulated genes presented in hPASCs and the tumor cells. Those upregulated genes (Log₂FC > 1, p < 0.05) were represented as red dots while downregulated ones were in blue (Log₂FC < -1, p < 0.05). C KEGG enrichment of differentially expressed genes between hPASC and the matched tumor cells. (D-E) GO analysis of differentially expressed genes between hPASC and the matched tumor cells