Fig. 2
From: Identification and gene expression profiling of human gonadotrophic pituitary adenoma stem cells
Human gonadotrophic adenoma stem cells possessed the capacity of differentiation. A Immunostaining of FSH and Sox2 in hPASCs and the differentiated daughter cells. Compared to the hPASCs, the differentiated cells expressed a much lower level of Sox2 but strong FSH. B Representative images of hPASCs and the differentiated cells. C Quantification of cell number between hPASCs and the differentiated cells. After 5-day differentiation, the number of cells in the differentiated group was significantly higher than the hPASC group. (**p < 0.005; n = 4 independent experiments). D Measurement of FSH level in the hPASC and the differentiated cells by ELISA. The level of FSH in the differentiated cells was not significantly changed compared to the hPASC group (p > 0.05; n = 4 independent experiments). d-cells: differentiated cells. Scale bar is 100um for all panels