Fig. 10

Correlations between DTI derived fractional anisotropy from manual and whole brain segmented analyses and behavior. Green circles represent individuals from the sham group and purple squares are the individuals from the jmTBI group. A Higher FA in the ipsilateral CA1 region correlated with poor learning (longer cumulative distance) during spatial learning task 1 (SL, A) of the MWM. B Increased FA in the ipsilateral CA1 region negatively correlated with worse memory (lower DI) during the NL test. C, D Decreased FA in the ipsilateral (C) and contralateral (D) SI/NB postively correlated with poorer memory (lower DI) during the NL test. Linear regression. Dashed lines represent intervals of confidence. E Pearson correlation coefficients between spatial memory test outcomes and DTI values from whole brain segmentation analyses for ipsi- and contralateral CA1, DG, SI and NBM. The heatmap shows in red positive and in blue negative correlations, with significant differences inidcated by an asterisk (P < 0.05). Several DTI values in the 4 ROIs ipsi- and contra lateral are correlated with behavioral scores