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Fig. 1 | Acta Neuropathologica Communications

Fig. 1

From: Reduced T-cell densities in cranial nerves of patients who died with SARS-CoV-2 infection

Fig. 1

CD3+ T-cells in olfactory tract and cranial nerves V, VII and X in postmortem controls and SARS-CoV-2-infected patients. a Conventional haematoxylin–eosin staining (HE) and immunohistochemistry for neurofilament protein, CD3 and CD8 in a cross section of a control trigeminal nerve. Scale bar = 100 µm. b Quantification of CD3+ T-cell density in olfactory tract, cranial nerve V, VII and X in controls (n = 52) and SARS-CoV-2 infected patients (n = 38). Mann–Whitney test was used due to unequal variances. c No correlation between age and mean CD3+ T-cell density in controls (n = 57) and SARS-CoV-2 infected patients (n = 38); values as mean of CD3+ T-cell density in nerves V, VII and X. d Correlation between CD8+ and CD3+ T-cell densities in those nerves V, VII and X with CD3+ T-cell densities of at least 20/mm2 in controls and SARS-CoV-2-infected patients

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