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Fig. 1 | Acta Neuropathologica Communications

Fig. 1

From: Cerebellar granule neurons induce Cyclin D1 before the onset of motor symptoms in Huntington’s disease mice

Fig. 1

S4-HdhQ200 mice have a mild behavioral phenotype. A, B Body weight is not significantly reduced in male (A), or female (B) HD mice compared to littermate controls. C HD mice remain on the rotarod for less time than control mice at 15 months. D, F HD mice show no significantly different performance in the balance beam task. For each time point, two repeat measures were performed, with a one-hour burrowing period between the first (D) and second (F) test. E HD mice burrow less than littermate controls at 9 months and 12 months. HD n = 12 (green), control n = 7 (black), unpaired t-test without corrections for multiple testing, (*p < 0.05)

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Acta Neuropathologica Communications

ISSN: 2051-5960

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