Fig. 9

A Representative images of immunohistochemistry of AQP4 antibody acquired with Axioscan microscope in wild type mice. Scale bar 1000 μm. B, C Histograms of AQP4 and GFAP density respectively analyzed through the percentage of pixels, after the same threshold is set for all the region of interests. NF not fragmented mice, F fragmented mice, LS lateral septum, RSC retrosplenial cortex, MSC motor-sensory cortex, DG dentate gyrus, TH thalamus, HY hypothalamus, BLA basolateral amygdala. The data are mean standard error of the mean (SEM). Each data point represents an individual animal. **p < 0.01; ***p < 0.005 versus control by ANOVA followed by Bonferroni post-hoc test, n = 4 per condition