Fig. 2

A Time spent in both closed and open arms during the EPM test. B Distance traveled in closed and open arms, and in the total arena during the EPM test. C Distance traveled in arena, border, and center in the OF test. D Time spent in both the border and the center of the arena during the OF test. E Behavioral activities during the OF test (protective and un-protective rearing). NF not fragmented mice, F fragmented mice. The data are mean standard error of the mean (SEM). Each data point represents an individual animal. *p < 0.05; **p < 0.01; ***p < 0.005; ****p < 0.0001 versus control by one-way ANOVA followed by Fisher’s LDS post-hoc test, n = 11 per condition