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Fig. 5 | Acta Neuropathologica Communications

Fig. 5

From: Hydrogen peroxide induced by nerve injury promotes axon regeneration via connective tissue growth factor

Fig. 5

Sciatic nerve injury drives increased Ctgf levels. A Longitudinal views of whole mount preparations of sciatic nerves from control mice (Ctr, upper panels), four days after nerve compression (crush, middle panels), and six days after nerve transection (cut, lower panels). Dotted lines indicate the injury site. Ctgf is in red and SCs are GFP-positive (green). Scale bar: 100 µm. B, D Cross-sections of sciatic nerves in control conditions (Ctr, upper panels), four days after nerve compression (B), and six days after nerve transection (D). SCs are GFP-positive (green), NF in white, Ctgf is in pseudocolors. A pseudocolor scale is added in the corresponding figures, where white corresponds to the highest intensity, and black to the lowest. Scale bars: 50 µm. C, E Quantification of Ctgf signal in cross sections. N = 3, *p = 0.041 (C), **p = 0.003 (E)

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