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Table 1 Participant characteristics and demographic information

From: Differential vulnerability of the dentate gyrus to tauopathies in dementias

 

PPA-PiD (N = 8)

PPA-CBD (N = 8)

PPA-PSP (N = 8)

PPA-AD (N = 8)

DAT-AD (N = 5)

Overall (N = 37)

Sex (% Female)

50%

62.5%

62.5%

25%

60%

51%

Age at Onset (yrs; mean ± SD)

59 ± 4.9

64.9 ± 4.5

71.3 ± 6.6

62.3 ± 10.1

70.2 ± 9.1

65.1 ± 8.3

Age at Death (yrs; mean ± SD)

69.8 ± 4.3

75 ± 6.6

80 ± 7.4

72.6 ± 9.1

81.4 ± 6.7

75.3 ± 7.9

Disease Duration (yrs; mean ± SD)

10.8 ± 2.5

10.1 ± 3.9

8.8 ± 2.9

10.4 ± 3.3

11.2 ± 4.1

10.2 ± 3.2

PMI (hrs; mean ± SD)

12.9 ± 10.5

15.6 ± 14.2

19.3 ± 20.4

14.3 ± 6.8

21.8 ± 28.2

16.3 ± 15.9

Brain Weight (g; mean ± SD)

1011.6 ± 91.2

1112.1 ± 118.8

1179.6 ± 130.4

1151.7 ± 150.7

1178 ± 147.2

1119 ± 134

Education (yrs; mean ± SD)

15.6 ± 2.4

16.3 ± 2.3

15.5 ± 2.1

16.5 ± 2.6

14.4 ± 2.6

15.8 ± 2.3

ApoE 4 Frequency (%)

14.3%

7.1%

6.3%

25%

50%

18.6%

  1. SD standard deviation, PPA primary progressive aphasia, PiD Pick’s Disease, CBD corticobasal degeneration, PSP progressive supranuclear palsy, AD Alzheimer’s Disease, DAT dementia of the Alzheimer’s type, PMI postmortem interval, ApoE apolipoprotein E