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Fig. 4 | Acta Neuropathologica Communications

Fig. 4

From: Cognitively impaired aged Octodon degus recapitulate major neuropathological features of sporadic Alzheimer’s disease

Fig. 4

AD-like degu hippocampus shows oligomeric Aβ deposits compared to age matched controls. Immunofluorescence confocal microscopic images show enhanced immunoreactivity of Aβ oligomers stained by mOC23 rabbit monoclonal antibody (red) in hippocampus of coronal sections (right hemispheres) of non-AD (a, b) and AD-like (c, d) degus. A zoom-in view of a part of CA1 in (c) and (d) is shown in (e, f). Arrows indicate selected mOC23-positive Aβ deposits. Counterstained with DAPI in blue. Note that overlap in DAPI (blue) and mOC23 (red) signal results in magenta color

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