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Fig. 1 | Acta Neuropathologica Communications

Fig. 1

From: Cognitively impaired aged Octodon degus recapitulate major neuropathological features of sporadic Alzheimer’s disease

Fig. 1

Degus behavioral burrowing performance as a screen for normal versus AD-like aged degus. a A photo of outbred degus in the colony directed by Dr. P. Cogram. b Representative images extracted from a video recorded during the degu performance of the burrowing test. c The cumulative distributions of the weights of pellets burrowed in 2 h (red curve) and in 6 h (blue curve). The (1) and (2) circles indicate the points of 0.25 and 0.75 cumulative data points for the 2-hour curve; the (1) and (2) circles indicate the points of 0.25 and 0.75 cumulative data points for the 6-hour curve (n = 146 degus, 4.5–5 years old). d Scatter plot showing the distribution of pellets burrowed after 2 h (red dots) and 6 h (blue dots) in the 6 age matched control degus and the 6 AD-like degus, all of which were neuropathologically examined in this study

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