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Fig. 3 | Acta Neuropathologica Communications

Fig. 3

From: CTCF loss induces giant lamellar bodies in Purkinje cell dendrites

Fig. 3

Loss of CTCF causes abnormal dendritic arborization with dendritic crossing in PCs. a Neurobiotin staining of a control and CTCF-cKO PC at P47-59 (left) and the resulting traced PCs (middle). A dendrite located in the region of the red box is shown at higher magnification (right) for each PC. Neurobiotin was injected into PCs as part of the patch-clamp recording process. Scale bars: 50 μm. be Quantitative analysis of the number of self-crossing dendrites (b), total area (c), number of branches (d), and total dendritic length (e). n = 8 neurons (control), n = 6 neurons (cKO). **p < 0.01, ***p < 0.005. Error bars represent the SEM

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