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Fig. 4 | Acta Neuropathologica Communications

Fig. 4

From: The enhanced association between mutant CHMP2B and spastin is a novel pathological link between frontotemporal dementia and hereditary spastic paraplegias

Fig. 4

Functional significance of the interaction between spastin and CHMP2BIntron5 in a Drosophila model of FTD3. a Representative images of fly eyes with different genotypes. b Quantification of the retinal degeneration phenotypes in CHMP2BIntron5-expressing flies with or without spastin knockdown. The number of flies of each genotype is shown under the x-axis. The percentages of flies with severe, medium, or weak eye phenotypes are shown in the columns. ****p < 0.0001 by chi-square analysis

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Acta Neuropathologica Communications

ISSN: 2051-5960

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