Acta Neuropathologica Communications

Table 2 Summary of r-mTBI and PFF induced PD like pathology in the SNpc

From: Repetitive mild TBI causes pTau aggregation in nigra without altering preexisting fibril induced Parkinson’s-like pathology burden

	Left				Right
	pTau	aSyn	TH loss	Iba1 + MHCII	pTau	aSyn	TH loss	Iba1 + MHCII
8× r-mTBI + PFF	+++	0	0	+++	+++	+++	++	+++
PFF	+	0	0	0	+++	+++	++	++
8× r-mTBI + Mono	+++	0	0	+++	+++	0	0	+++
8× r-mTBI	+++	0	0	+++	+++	0	0	+++
4× r-mTBI	+	0	0	0	+	0	0	0
Sham	+	0	0	0	+	0	0	0

Relative abundance of pathology is listed in descending order of burden in the left and the right side of the brain. For rats that underwent intracranial injection, right side is ipsilateral to the injection

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ISSN: 2051-5960

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