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Fig. 2 | Acta Neuropathologica Communications

Fig. 2

From: Molecular and spatial heterogeneity of microglia in Rasmussen encephalitis

Fig. 2

Gene expression signatures of microglia in Rasmussen encephalitis. a Volcano plot showing differentially expressed genes in RE vs CTRL (DESeq2 adjusted p-value < 0.05, FC > 1.5). Labeled genes are shown on heatmap in Fig. 2c. b Volcano plot showing differentially expressed genes in RE vs FCD (DESeq2 adjusted p-value < 0.05, FC > 1.5). Labeled genes are shown on heatmap in Fig. 2d. c Heatmap showing individual gene contribution (via positive fold-change) to GO biological process annotation enrichment in RE vs CTRL. d Heatmap showing individual gene contribution (via positive fold-change) to GO biological process annotation enrichment in RE vs FCD. e–g Selections from KEGG Pathways: TNF signaling pathway e, Antigen processing and presentation f and Cell adhesion molecules g highlighting differentially high expression of genes in RE vs both CTRL and FCD controls

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