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Fig. 2 | Acta Neuropathologica Communications

Fig. 2

From: Methylation differences in Alzheimer’s disease neuropathologic change in the aged human brain

Fig. 2

UMAP plot displaying clustering of brain region and cell-type-specific methylation data. We used the Uniform Manifold Approximation and Projection (UMAP) technique for dimension reduction to visualize similarities across cell type and brain-region-specific methylation data. Dimensionality reduction is performed with all brain regions and cell types combined. Each dot represents one individual sample. Colors reflect the cell types. Olig Oligodendrocytes, OPC Oligodendrocyte Precursor Cells, MFG Middle Frontal Gyrus, CG Cingulate Gyrus, CA1 Hippocampus CA1, DG Dentate Gyrus, EC Entorhinal cortex, SN Substantia nigra, LC Locus coeruleus, CBM Cerebellar cortex

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