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Table 1 Diagnoses of cohort patients along with sex distribution for cases of infiltrating glioma and average age of diagnosis for infiltrating gliomas

From: Towards a single-assay approach: a combined DNA/RNA sequencing panel eliminates diagnostic redundancy and detects clinically-relevant fusions in neuropathology

Total number of patients for all tumor classes

 

Diffuse astrocytoma, IDH-wildtype, presenting in adult patients

112

            Glioblastoma, IDH-wildtype (grade 4 histology)

99

            Glioblastoma, IDH-wildtype (lower grade histology)

9

            (Pediatric-type) Diffuse hemispheric glioma, H3G34-mutant

3

Diffuse astrocytoma, IDH-wildtype, NOS

1

Astrocytoma, IDH-mutant

29

Neuroepithelial Tumor, NOS

16

Oligodendroglioma

14

Pilocytic Astrocytoma

11

Diffuse gliomas, presenting in pediatric patients

6

            Diffuse midline glioma, H3K27M mutant

4

            Diffuse hemispheric glioma, H3G34-mutant (pediatric patients)

2

Astrocytoma, NOS

6

Meningioma

5

Ganglioglioma

4

Dysembryoplastic Neuroepithelial Tumor (DNET)

3

Ependymoma

3

Medulloblastoma

2

Non-Diagnostic

2

Solitary Fibrous Tumor/Hemangiopericytoma (SFT/HPC)

2

Central Neurocytoma

1

Cortical Dysplasia

1

Craniopharyngioma

1

Diffuse Leptomeningeal Glioneuronal Tumor (DLMGNT)

1

Dysplastic Cerebellar Gangliocytoma

1

Embryonal Tumor with Multilayered-Rosettes, C19MC-altered

1

(ETMR, C19MC-altered)

1

Endodermal Cyst

1

Epilepsy

1

Malignant Neoplasm, NOS

1

Meningioangiomatosis

1

Pilomyxoid Astrocytoma

1

Pineal Parenchymal Tumor of Intermediate Differentiation (PPTID)

1

Pituicytoma

1

Reactive

1

Schwannoma

1

Tuber

1

Sex of infiltrating glioma cases in adults

Oligodendroglioma

 

M

10

F

4

IDH-mutated Astrocytoma

 

M

20

F

9

Diffuse astrocytomas, IDH-wildtype

 

M

51

F

61

Average age at diagnosis for infiltrating glioma cases in adults

Oligodendroglioma

48.5 ± 13.5

Astrocytoma, IDH-mutant

38.2 ± 12.1

Diffuse astrocytomas, IDH-wildtype

61.9 ± 13.0