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Fig. 3 | Acta Neuropathologica Communications

Fig. 3

From: Towards a single-assay approach: a combined DNA/RNA sequencing panel eliminates diagnostic redundancy and detects clinically-relevant fusions in neuropathology

Fig. 3

CDKN2A alterations detected on the Oncomine targeted NGS panel. A Distribution tumor classes in which each type of alterations detected in CDKN2A was found (DMG_H3K27M = Diffuse midline glioma, H3K27M mutant; GG = Ganglioglioma; IA_IDH_MUTANT = IDH-mutant infiltrating astrocytoma; IA_IDH_WT = IDH-wildtype infiltrating astrocytoma in adult patients; IA_IDH_WT_PEDIATRIC = Infiltrating astrocytomas in pediatric patients, IDH-wildtype; MALIGNANT_NEOPLASM_NOS = malignant neoplasm, not otherwise specified; MENINGIOMA = meningioma; NET_NOS = Neuroepithelial tumor, not otherwise specified; OLIGO = Oligodendroglioma). B Types of CDKN2A alterations found in each subgroup of infiltrating glioma. C Spread of copy number of CDKN2A by tumor class where each point represents a case which is colored by the CDKN2A alteration class called by the Oncomine panel. D distribution of copy number of CDKN2A for subgroups of infiltrating glioma

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