Fig. 4
From: Reversal of cancer gene expression identifies repurposed drugs for diffuse intrinsic pontine glioma
Comparison of the effects of mycophenolate mofetil (MMF) and mycophenolic acid (MPA) in DIPG cells. A Left: Graphs showing the proliferation response of SU-DIPG-IV, to increasing concentrations of MMF and MPA for 3 days treatment. Values shown are the average (mean ± SD) from triplicate samples for each incubation condition. Right: Dot plot representation of IC50 values shown are the average (mean ± SD) from triplicate samples for each treatment condition. B Left: Graphs showing the proliferation response of SF8628, to increasing concentrations of MMF and MPA treatment. Values shown are the average (mean ± SD) from triplicate samples for each incubation condition. Right: Dot plot representation of IC50 values shown are the average (mean ± SD) from triplicate samples for each treatment condition. Statistical analysis was performed using a two-tailed unpaired t-test. No significant differences were found among MMF and MPA