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Fig. 1 | Acta Neuropathologica Communications

Fig. 1

From: A case of primary optic pathway demyelination caused by oncocytic oligodendrogliopathy of unknown origin

Fig. 1

MRI at 3 (A–K) and 7 Tesla (L–N). A–C Initial MRI study. A The FLAIR image shows a hyperintense lesion in the right temporal lobe with a strongly hyperintense center and a perilesional zone of intermediate hyperintensity. B Post-contrast T1 image revealed slight contrast enhancement in the lesion center and T1-hypointensity in the perilesional zone, most likely corresponding to perilesional edema. C Diffusion map with facilitated diffusion in the perilesional area and largely unaltered diffusion metrics in the lesion center. D–G Serial axial FLAIR images and H–K serial coronal T2-weighted images after biopsy show a largely stable lesion which remains strictly confined to the white matter. Two biopsy sites are visible in the lesion. L 7 Tesla FLAIR image reveals a lesion situated in the white matter and partly sparing the subcortical U fibers. M T1-weighted MP2RAGE image identifies a homogeneously hypointense lesion area. The biopsy site is surrounded by an area of increased signal, which might be related to the biopsy procedure. N SWI shows the biopsy site within a lesion of homogenous high signal intensity. The biopsy site itself is characterized by patchy hypointense signal alterations, likely reflecting extravasation of blood products due to the biopsy

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