Skip to main content
Fig. 5 | Acta Neuropathologica Communications

Fig. 5

From: The role of plasminogen activator inhibitor-2 in pneumococcal meningitis

Fig. 5

PAI-2 mRNA expression (a), as well as PAI-2 (b) and IL-10 release (c) into the cell culture supernatant of wt and PAI-2-deficient BMDM upon pneumococcal challenge. Pneumococcal exposure led to strong upregulation of PAI-2 mRNA expression (a) and increased PAI-2 release by wt BMDM (b). PAI-2-deficient BMDM responded to S. pneumoniae challenge by decreased IL-10 liberation compared to wildtype BMDM (C). Todd Hewith Broth with yeast (THY), culture medium for S. pneumoniae, was used as a control

Back to article page