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Fig. 1 | Acta Neuropathologica Communications

Fig. 1

From: The role of plasminogen activator inhibitor-2 in pneumococcal meningitis

Fig. 1

CSF PAI-2 levels (a) of patients included in the Dutch bacterial meningitis cohort with PM. Immunohistochemical analysis with PAI-2 of human brain sections obtained from uninfected control cases (b) and PM cases (c). Murine CSF (d) and plasma (e) PAI-2 levels 24 and 48 h after induction of PM. Immunohistochemical analysis with PAI-2 of murine brain sections obtained from uninfected control cases (f) and PM cases (g). The sections were stained with a PAI-2 antibody and counterstained with hematoxylin–eosin. Both human and murine immunohistochemical examination showed strong PAI-2 staining in the inflammatory infiltrate in the leptomeningeal space. The scale bar indicates 100 µm in length

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