From: Stem cell phenotype predicts therapeutic response in glioblastomas with MGMT promoter methylation
Characteristic | HR PFS | P PFS | HR OS | P OS |
---|---|---|---|---|
Univariate | ||||
Age (continuous variable) | – | 0.2 | 1.03 (1.01–1.06) | 0.02 |
Age (Categorical variable: > or < 62) |  | 0.4 | 1.8 (1.1–3.1) | 0.03 |
MGMT promoter methylation status (n = 72)* | 0.5 (0.28–0.9) | 0.02 | 0.47 (0.26–0.88) | 0.02 |
Gender | – | 0.8 | 0.56 (0.3–0.97) | 0.04 |
Resection | – | 0.08 | – | 0.7 |
CD133 | – | 0.6 | – | 0.8 |
SOX2 | – | 1.0 | – | 0.9 |
NES Percentage | – | 0.8 | – | 0.4 |
NES blood vessels | – | 0.6 | – | 0.5 |
Multivariate | ||||
Gender | 1.2 | 0.7 | 0.6 (0.3–1.1) | 0.1 |
Age (Categorical variable: > or < 62) | 0.4 | 1.4 | 1.9 (1.0–3.6) | 0.05 |
MGMT Promoter Methylation (n = 72)* | 0.02 | 0.4 (0.2–0.9) | 0.5 (0.4–1.3) | 0.04 |