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Fig. 1 | Acta Neuropathologica Communications

Fig. 1

From: Artificial intelligence-derived neurofibrillary tangle burden is associated with antemortem cognitive impairment

Fig. 1

Detection of neurofibrillary tangles (NFT) in phospho-tau (AT8) immunohistochemically stained whole slide images (WSI). a Example of a hippocampal WSI immunohistochemically stained for phosphorylated-tau (AT8). The hippocampus proper (blue) and entorhinal region (red) were manually segmented. b High-power (20x) representative image of the hippocampal CA2 subfield showing p-tau positive neurofibrillary tangles. c Corresponding output of above image passed through semantic segmentation model that identifies NFT. Each pixel value corresponds to the probability that it represents an NFT

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Acta Neuropathologica Communications

ISSN: 2051-5960

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