Skip to main content
Fig. 6 | Acta Neuropathologica Communications

Fig. 6

From: Dysregulation of neuroprotective astrocytes, a spectrum of microglial activation states, and altered hippocampal neurogenesis are revealed by single-cell RNA sequencing in prion disease

Fig. 6

Sub-cluster analysis of astrocytes reveals disease-depleted and disease-associated subtypes during prion disease. A UMAP projection of all 7,813 astrocytes categorized into 11 sub-clusters. B Violin plots showing expression of Gfap and Nrxn3 across each astrocyte sub-cluster. C The relative frequency of each astrocyte sub-cluster is plotted for the cortex and hippocampus of RML and Mock infected mice. p values s were calculated using non-parametric Mann–Whitney U tests. * p values  < 0.1, ** p values  < 0.05, *** p values  < 0.01. All p values are provided in Additional file 6

Back to article page

Acta Neuropathologica Communications

ISSN: 2051-5960

Contact us