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Fig. 3 | Acta Neuropathologica Communications

Fig. 3

From: Dysregulation of neuroprotective astrocytes, a spectrum of microglial activation states, and altered hippocampal neurogenesis are revealed by single-cell RNA sequencing in prion disease

Fig. 3

Differences in relative frequency of cell populations isolated from the cortex and hippocampus of RML infected mice compared to mock infected mice. The relative frequency of each cell cluster is plotted for the cortex and hippocampus of RML and mock infected mice. p values s were calculated using the non-parametric Mann–Whitney U tests. * p values  < 0.1, ** p values  < 0.05, *** p values  < 0.01. All p values are provided in Additional file 5. astro—astrocytes; endo—endothelial cells; g.neu—mature glutamergic neurons; im.neu—immature neurons; micro—microglia; opc—oligodendrocyte progenitor cells; pvm—perivascular macrophages; epen—ependymal cells; lymph—lymphocytes; cx—cortex; hp—hippocampus

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