Fig. 3
From: Müller cell degeneration and microglial dysfunction in the Alzheimer’s retina
Layer-wise retina Aβ load in Alzheimer’s disease (AD) retina compared to controls. Red bars represent AD donors (N = 5). Blue bars represent age-matched controls (N = 7). BA4 labelled post-mortem human retina cross-sections were imaged at central and mid-peripheral locations in relation to optic nerve head. Normalized area percentage of BA4 labelled Aβ was calculated in each retinal layer and plotted against the particular layer. Aβ was significantly higher in the AD donors in the mid-peripheral GCL (p < 0.05), IPL (p < 0.01), INL (p < 0.05), and OPL (p < 0.05). However, in central retina there was no significant differences between AD and control retina. * represent p < 0.05. ** represent p < 0.01. Error bars = Standard Error