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Fig. 1 | Acta Neuropathologica Communications

Fig. 1

From: Posterior fossa ependymoma H3 K27-mutant: an integrated radiological and histomolecular tumor analysis

Fig. 1

Cohort characteristics. Based on H3K27me3 immunohistochemistry, 116 cases were classified as EPN_PFA showing a loss of immunoexpression, and 31 were EPN_PFB with a conserved H3K27me3 expression. From the 116 EPN_PFA, 108 were immunopositive for EZHIP and eight cases were immunopositive for the H3K27M mutation. From the national French Neuropathological Reference network (RENOCLIP-LOC) database, we found one additional pediatric case of EPN_PFA with H3K27M immunopositivity. Scale bars represent 50 µm

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