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Table 3 Human brain tissues of corticobasal degeneration, Pick's disease, and progressive supranuclear palsy cases used in this study

From: Tau seeding activity in various regions of down syndrome brain assessed by two novel assays

Diagnosis

Case #

Age (Year)

Gender

PMI (h)

Pathology

Causes of death

CBD

TN10-34

81

F

3.5

CBD

Acute hypoxic respiratory failure secondary to pneumonia

CBD

TN09-27

84

M

12

CBD

Cardiac Arrest

CBD

TN15-09

95

M

11

CBD

Complications of inanition secondary to severe cognitive decline

PiD

TN15-83

83

F

12

FTLD-tau, A3, B3, C3, subacute infarctions

Complications of inanition secondary to severe cognitive decline

PiD

TN12-17

83

M

12

FTLD-tau, hippocampal sclerosis,A1, B1, C1

Complications of inanition secondary to severe cognitive decline

PiD

TN15-06

87

M

18

FTLD-tau, A0, B1, C0

Complications of inanition secondary to severe cognitive decline

PSP

TN15-85

95

M

15

PSP, A2, B2, C2

Asphyxia secondary to aspiration episode

PSP

TW19-31

72

M

16

PSP, A3, B3, C3, right frontal lobe remote infarction

Complications of inanition secondary to severe cognitive decline

  1. Frozen brain tissues were obtained from the New York University Alzheimer’s Disease Research Center
  2. PMI, postmortem interval; CBD, corticobasal degeneration; PiD, Pick's disease; FTLD-tau, frontotemporal lobar degeneration with tau pathology; PSP, progressive supranuclear palsy