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Fig. 5 | Acta Neuropathologica Communications

Fig. 5

From: α-Dystrobrevin knockout mice have increased motivation for appetitive reward and altered brain cannabinoid receptor 1 expression

Fig. 5

mRNA levels of dystrobrevin binding protein 1, dopamine, mu opioid and cannabinoid receptors. No differences were noted between WT and α-DB KO mice in mRNA levels of dystrobrevin binding protein 1 (Dtnbp1) (a), dopamine transporter (Scl6a3) (b), dopamine receptor 1 (Drd1a) (c), dopamine receptor 2 (Drd2) (d) or cannabinoid receptor 1 (Cnr1) (e). mu Opioid receptor 1 (Oprm1) levels were significantly decreased in the nucleus accumbens (nAc) and caudate-putamen (Cpu) of KO mice relative to WT animals (f). PfCtx = prefrontal cortex, Tegmtm = tegmentum. *p < 0.001, two-way ANOVA with Sidak’s post-hoc

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