Fig. 2

Behavioural outputs of WT and α-DB KO mice on the PVD task. No significant differences were observed between α-DB KO mice and WT mice on days to criteria (correct identification of rewarding stimulus in ≥ 80% of trials) during acquisition (a) and reversal (b) of the task. In addition, the rate of learning, as determined by the daily % of animals that have not reached criteria, was similar between WT and KO mice in both acquisition (c) and reversal (d). Reward collection latency did not differ between WT and KO mice in either phase of training (e). The number of trials in which performance was < 50% correct and ≥ 50% correct during the reversal sessions differed between WT and KO mice (f). n = 12/group. For a and b, p > 0.05, two-tailed t-test. For c and d, p > 0.05, log-rank (Mantel-Cox) test. For e and f, *p < 0.05, two-way repeated measures ANOVA with Sidak’s post-hoc