Fig. 11
From: Protein citrullination marks myelin protein aggregation and disease progression in mouse ALS models
Myeline proteins, PLP, MBP, and MAG, but not MOG are enriched in insoluble protein aggregates in lumbar spinal cord. Filter trap assay and quantification of optical density of PLP (A, B), MBP (C, D), MAG (E, F), and MOG (G, H), in SOD1G93A and PFN1C71G ALS mice, respectively. All animals are at paralysis stage. n = 4 in each group. Statistics: unpaired t test for comparing transgenic mice with their age matched nTg controls. *p < 0.05; **p < 0.01; ***p < 0.001. n.s., not significant