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Table 1 Study sample used for linear regressions, correlations and graphical lasso (N = 230)

From: LATE-NC aggravates GVD-mediated necroptosis in Alzheimer’s disease

Variable

Frequency

Mean

Age

67 years (range 25–96 years)

Male/Female

127 (55%)/ 103 (45%)

Not applicable

Neuropathological diagnosis

Non-ADNC

82 (37%)

Not applicable

p-preAD

81 (36%)

Demented ADNC

67 (27%)

Cognition

Non-impaired

83 (47%)

Not applicable

Dementia

95 (53%)

Not available

52

Braak NFT Stage

0

40 (17%)

II

I

68 (30%)

II

36 (16%)

III

19 (8%)

IV

25 (11%)

V

20 (9%)

VI

22 (9%)

AβMTL Phase

0

87 (38%)

2

1

20 (9%)

2

20 (9%)

3

29 (12%)

4

74 (32%)

LATE-NC Stage

0

132 (58%)

1

1

10 (4%)

2

62 (27%)

3

26 (11%)

GVD Stage

0

112 (51%)

1

1

39 (18%)

2

12 (5%)

3

12 (5%)

4

28 (13%)

5

18 (8%)

CDR Score

0

83 (47%)

1

0.5

8 (4%)

1

22 (12%)

2

19 (11%)

3

46 (26%)

Not available

52

CERAD Score

0

149 (65%)

1

1

21 (9%)

2

34 (15%)

3

26 (11%)

APOE status

2/2

1 (1%)

Not applicable

2/3

14 (10%)

3/3

73 (53%)

3/4

40 (29%)

4/4

10 (7%)

Not available

91

  1. Number of cases assessed for each variable: age, sex, Braak NFT stage, AβMTL phase, LATE-NC stage, GVD stage, CERAD score = 230; Cognition/CDR score = 178; APOE status = 139