Fig. 3
From: Lymphatic vessels are present in human saccular intracranial aneurysms
Representative images of immunofluorescence double stainings for A LYVE-1 (green) and CD68 (red), B podoplanin (green) and αSMA (red), and C VEGFR-3 (green) and αSMA (red) in three saccular intracranial aneurysm walls. Double-positive staining (yellow) is indicated with a red arrow in panels A and C. LYVE-1- and podoplanin-positive stainings (green) are indicated with green arrowheads in panels A and B, respectively. Positive staining for αSMA (red) is indicated with red arrowheads in panels A and B. Green ring-shaped structure positive for podoplanin and negative for αSMA demonstrates a lymphatic vessel and red ring-shaped structure positive for αSMA and negative for podoplanin demonstrates a vascular neovessel in panel B. The negative controls are shown as insets. White arrows point down towards the lumen. Scale bar: 50 μm