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Table 1 Patient clinical characteristics

From: Redefining germline predisposition in children with molecularly characterized ependymoma: a population-based 20-year cohort

Patient characteristics

n (% of total)

Total

43 (100%)

Median age at diagnosis, y (SD)

5.3 (4.7)

 Status

 

  Alive

27 (62.8%)

  Deceased

16 (37.2%)

 Gender

 

  Female

19 (44.2%)

  Male

24 (55.8%)

 Cohort

 

  Retrospective

34 (79.1%)

  Prospective

9 (20.9%)

 Histopathological diagnosis

 

  Myxopapillary ependymoma, WHO 2

1 (2.3%)

  Ependymoma, WHO 2

14 (32.6%)

  Ependymoma, WHO 3

26 (60.5%)

  Other*

2 (4.7%)

 Tumor location

 

  Supratentorial

7 (16.3%)

  Posterior fossa

30 (69.8%)

  Spinal

5 (11.6%)

  Multifocal**

1 (2.3%)

  1. *Includes one patient initially diagnosed with atypical glioblastoma for whom subsequent clinical tumor methylation profiling resulted in an ependymoma diagnosis and one patient with ependymoblastoma incorrectly registered as ependymoma
  2. **Includes one patient with disseminated ependymoma at diagnosis with tumor tissue located adherent to the insular cortex, the ventral surface of the brainstem and the caudal spinal cord
  3. SD, standard deviation; y, years; WHO, the World Health Organization histological grade