Table 2 Differently expressed proteins across brain regions in early PD (Braak stage 3/4) compared to controls
From: Mitochondrial dysfunction is a key pathological driver of early stage Parkinson’s
Upregulated | Downregulated | Total | |
|---|---|---|---|
Substantia nigra | 159 | 301 | 460 |
Caudate | 59 | 63 | 122 |
Putamen | 69 | 96 | 165 |
Parahippocampus | 72 | 100 | 172 |
Temporal cortex | 45 | 64 | 109 |
Cingulate cortex | 60 | 63 | 123 |
Frontal cortex | 118 | 93 | 211 |
Parietal cortex | 55 | 70 | 125 |
Cerebellum | 58 | 70 | 128 |