Fig. 9
From: Mitochondrial dysfunction is a key pathological driver of early stage Parkinson’s
Progression of mitochondrial protein expression changes through the early PD brain. Schematic showing how mitochondrial proteins change in expression through the areas of the brain that are affected by alpha-synuclein pathology in early stage PD. Green represents downregulated proteins and red represents upregulated proteins when compared to controls. Arrows represent severity of the pathology across regions of the brain. Middle brain image represents how the pathology has spread through the brain at Braak stage 3/4 (adapted from [85]) Mitochondrial expression diagrams were made using IPA software. Figure made with biorender.com