Fig. 4

Exome sequencing of GBM CD105⁺ cells. A The number of mutations, annotated genes and the rate of mutant genes matching into the CCLE cancer database were analyzed from the exome sequencing data of 5 GBM CD105⁺ cell lines. Pie chart quantifying the subtype of mutations. B Circos chart showing the distribution of mutant genes in each chromosome. The area represents the number of mutant genes. C Veen chart displaying common mutant genes among 5 GBM CD105⁺ cell lines. D Mutant genes matching TCGA and CCLE databases. E The mutant genes of GBM CD105⁺ cells matching with GBM hallmark genes from COSMIC. Upper panel: Representation of mutation types. Lower panel: Subclone variant allele frequencies (VAF)