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Fig. 3 | Acta Neuropathologica Communications

Fig. 3

From: Modeling the early stages of Alzheimer’s disease by administering intracerebroventricular injections of human native Aβ oligomers to rats

Fig. 3

Anxiety-related behaviors assessed using the EPM test. Rats were i.c.v. injected with AD or non-AD control extracts (n = 12 per group) and tested in the EPM for 10 min on Day 17 postinjection. A Time spent in the closed and open arms and in the central square expressed as percentage of total time. B Latency to the first entry into an open arm. C Total distance traveled and total number of arm entries were similar between the AD and control groups. D Percentage of time spent in the closed and open arms and the central square analyzed for each 2.5 min time interval. Data are presented as the means ± SEM. *p < 0.05

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Acta Neuropathologica Communications

ISSN: 2051-5960

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