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Table 1 Neuropsychological performance and functional decline over time

From: Focal amyloid and asymmetric tau in an imaging-to-autopsy case of clinical primary progressive aphasia with Alzheimer disease neuropathology

Visit

WAB-AQ

(100)

WAB-Rep

(66)

BNT

(60)

PPVT

(36)

NAT-nc

(15)

Rivermead

(10)

CDR-global

(*)

CDR-language (*)

ADLQ

(100)

NPI-Q

severity

(36)

Baseline

68.30

23

39

35

2

10

0.5

2

34.85

1

6-month

54.50

19

25

27

4

10

0.5

2

42.11

3

12-month

39.80

5

22

32

N/A

8

0.5

2

46.67

6

18-month

35.10

1

0

21

0

8

1

3

54.67

7

  1. Neuropsychological performance and functional questionnaire at each visit. WAB = Western Aphasia Battery; WAB-AQ = WAB aphasia quotient; WAB-Rep = WAB repetition subtest; BNT = Boston Naming Test; PPVT = Peabody Picture Vocabulary Test; NAT-nc = Sentence production scores on a composite of 15 noncanonical sentences from the Northwestern Anagram Test; Rivermead = Rivermead Behavioural Memory Test; CDR = Clinical Dementia Rating; ADLQ = Activities of Daily Living Questionnaire; NPI-Q severity = Neuropsychiatric Inventory-Questionnaire, sum of severity scores; N/A = not available. Higher numbers indicate better performance for the WAB-AQ, WAB-Rep, BNT, PPVT, NAT-nc, and Rivermead. * The CDR is an ordinal scale with possible values of 0, 0.5, 1, 2, or 3. Higher numbers the CDR-global (based on six cognitive domains) and CDR-language (language domain only) indicate increased impairment. Higher numbers on the ADLQ and NPI-Q indicate increased functional impairment