Fig. 5

Methylation-based classification of medulloblastoma is stable on all classification levels across time and space. Sankey plot of the medulloblastoma subgroup, determined without DNA methylation, based on the pathological-anatomical diagnosis (left), followed by the top methylation family, methylation class and subclass (right). The plot includes all spatial and temporal (primary and relapse) medulloblastoma samples where the subgroup had been determined in the clinic prior to DNA methylation classification