Fig. 8

Cardiac α-actin immunofluorescence. (A) Cardiac α-actin signals (Magenta) on muscle sections from patients and age-matched controls. Laminin appears in Cyan. Scale bar:100 \(\upmu \)m (B) Normal distribution of each fibre intensity for cardiac actin demonstrates an increased cardiac α-actin level in patients 6 and 7 compared with the other patients and the controls. The number of analysed fibres is indicated for each patient. (C) Western blot on muscle extracts shows intense cardiac α-actin bands in patients 7 and 8, and a lower expression in patient 2 and in the controls. Ponceau red served as loading control