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Table 3 Correlations of the ventral posterior (VP) subregion with OCT and neuroperformance measures in relapsing MS

From: Visual imaging as a predictor of neurodegeneration in experimental autoimmune demyelination and multiple sclerosis

Correlation with ventral posterior volume

n

Spearman rho coefficient

P

Median days

IQR days

Baseline OCT measures

  

Average Ganglion Cell-Inner Plexiform (GC/IPL)

62

0.43

0.0006

29.0

165.5

Peripapillary RNFL

67

0.44

0.0002

29.0

170.5

Macular RNFL

31

0.46

0.01

21.0

83.0

Macular volume

63

0.38

0.002

29.0

152.0

Outer retinal average thickness (macular scan)

31

0.002

0.99

21.0

83.0

Baseline Neuroperformance measures

  

Patient determined disease steps

747

 − 0.24

 < 0.0001

7.0

36.0

Dominant hand manual dexterity test

662

 − 0.30

 < 0.0001

5.0

33.0

Nondominant hand manual dexterity test

662

 − 0.33

 < 0.0001

5.0

33.0

Walking speed test

651

 − 0.28

 < 0.0001

5.0

33.0