Distinct cell type-specific protein signatures in GRN and MAPT genetic subtypes of frontotemporal dementia

Table 4 Number of unique peptides and proteins measured within the FTD cohort

Brain area	Group	QC Condition	Peptides (n)	Proteins (n)
Frontal, Temporal	NDC, FTD-GRN, FTD-MAPT	50% of all samples	9,545	2,040
Frontal	NDC, FTD-GRN	50% of NDC or FTD-GRN	12,939	2,400
	NDC, FTD-MAPT	50% of NDC or FTD-MAPT	11,958	2,346
Temporal	NDC, FTD-GRN	50% of NDC or FTD-GRN	9,425	2,037
	NDC, FTD-MAPT	50% of NDC or FTD-MAPT	9,123	2,010

Peptides and proteins are selected using quality value filtering on peptide level (see methods for details). Quality value peptide selection separated on brain area and FTD subtype gave the opportunity to analyse the highest number of proteins per statistical comparison

ISSN: 2051-5960